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p=0,001). One-year-incidence of PVT was 24% (10/41) and 11% (4/35) in HCC and
non-HCC patients, respectively (p=0,04). In the HCC group, 5/12 PVT occurred in
patients in Child Class A. ETP ratio in HCC patients was associated with PVT risk at
multivariate analysis (p<0.001).

Conclusions: Cirrhotic patients with HCC demonstrate a pro-thrombotic hemostatic
imbalance resulting in an increased risk of PVT development. Thrombin-generation test
seems to be a sensitive method to identify hypercoagulability, which would otherwise be
undetected by routine laboratory testing. Further investigations are needed to determine
whether patients with HCC should receive prophylactic anticoagulation for PVT
prevention.

Disclosure of Interest: None Declared

ePOSTER ABSTRACTS

240 Programme & Abstracts • HCC Summit